Optum life sciences UK

Research and Life Sciences

Optum sits at the heart of UK healthcare. Our clinical systems are relied on every day across primary care, pharmacy and community services — forming part of the national infrastructure that supports millions of patient interactions. Because our technology is woven directly into the systems clinicians already use, we’re not observing healthcare from the sidelines. We’re embedded within it — connecting people, pathways and data across the care ecosystem. This position gives us a unique ability to support researchers and life sciences organisations in turning innovation into real-world impact. From advancing clinical research, to enabling appropriate medicines and health technology adoption, to generating high-quality real-world insight, we help bridge the gap between evidence, policy and everyday practice — securely, responsibly and at scale. Together, we’re accelerating progress across medicine and healthcare — moving innovation closer to patients and the clinicians who care for them. Turning innovation into real world care

#1 clinical system supplier in:

Primary care used by 4,600+ GP practices*.

Community pharmacy used by 5,800+ pharmacies*.

A and E acute care used by 30 trusts*.

#2 clinical system supplier in:

Acute hospital pharmacy used by 63 hospital pharmacies*.

Community care used by 37 trusts*.

*Source: Optum

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Bringing effective treatments and technologies to life is complex — and too often, innovation struggles to make the leap from evidence to impact. Life sciences organisations face persistent challenges: • Recruitment into clinical trials is slow, unpredictable and often unrepresentative • Prescribers operate under extreme time pressure, with variation persisting across regions • Real-world data is costly, fragmented and frequently out of date • Reaching the right patients at the right moment is difficult • Regulatory and governance requirements make communication complex These challenges delay access, reduce equity and limit real-world value. Most approaches attempt to solve these problems from outside the healthcare system. Optum works differently — by operating inside the systems where care actually happens. Where innovation stalls

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Operating inside the UK healthcare system gives us a practical, day-to-day understanding of how innovation actually moves through care. As the leading provider of clinical systems across primary care, community pharmacy and community services, we’re embedded directly within the workflows where decisions are made, treatments are prescribed and patients are managed. From this position, we support research and life sciences organisations continuously — from early research through to routine use and ongoing evaluation — across many areas of the innovation lifecycle: Our ecosystem

Research and clinical trials

Enabling the appropriate uptake of medicines and technologies through in workflow clinical decision support, patient Medicines and health technology adoption

Real-world data and insight

Supporting clinical trial delivery and real-world research — from feasibility and site selection to participant recruitment and evidence generation in routine clinical settings.

Providing secure access to near real-time, longitudinal data to generate insight into disease burden, outcomes, variation and system performance at scale.

identification and pathway activation.

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Research and clinical trials Recruit is a powerful solution for clinical trial delivery and real-world research. Embedded in the UK’s leading GP clinical system and powered by rich primary care data, it supports trial sponsors across

Real-world research and evidence generation Recruit enables rapid, secure access to deidentified patient records from participating practices for approved research purposes. This supports high quality real-world evidence generation that reflects routine clinical practice, within a fully governed and compliant framework — complementing interventional trials and accelerating insight generation. Feasibility assessment and site selection Recruit feasibility uses real-world data to assess eligible, contactable patient populations before a study begins. This informs protocol design, identifies suitable primary care and community sites, and supports confident study setup. Recruit is fast and flexible, with rapid setup, adjustable cohorts and scalable engagement to match screening capacity. Explore the full brochure to find out more.

recruitment, evidence generation and feasibility. Clinical trial recruitment in primary care

Key stats: • 1,300+ GP practices using Recruit • 14+ million patients served by these practices

Recruit uses complex, protocol specific searches to analyse patient EHR data from consenting practices and identify eligible participants. With just a few clicks, GPs can access your study, surface eligible local patients and invite them to register interest via text or email. Optimised workflows — including secure healthcare record sharing and enrolment tracking — support efficient site engagement while reducing operational burden for practices and maintaining momentum across the study lifecycle.

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Medicines and health technology adoption We support the appropriate adoption of medicines and health technologies by operating directly within everyday clinical workflows. Through our clinical systems and digital capabilities, we help translate evidence and guidance into consistent, safe and scalable clinical practice. Powered by real-world clinical data and delivered at the point of care, our capabilities support adoption across three key areas: In workflow clinical decision support Prompts, alerts and guidance are embedded directly within the clinical systems clinicians already use, supporting timely, evidence based decision making at the point of care. Relevant information is delivered in context, enabling informed choices without disrupting routine practice.

Guideline aligned therapy implementation We support the appropriate uptake of guideline recommended medicines and health technologies by enabling consistent implementation across clinical teams and care settings. This helps reduce unwarranted variation and supports more equitable adoption across populations. Proactive patient identification and pathway activation Using real-world clinical data, we support the identification of at risk or undertreated patients and support their timely entry into appropriate care pathways. This enables earlier intervention and more consistent, pathway led care aligned to evidence and best practice. Together, these capabilities help ensure medicines and health technologies move from approval to appropriate use — embedded within everyday clinical care.

Our impact includes: • Improved dosing accuracy in heart failure • Proactive

identification of Hep C risk cohorts

• Kidney failure risk prediction at scale • Accelerated AF

pathway optimisation and referrals

Explore the full brochure to find out more.

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Population level disease and outcomes insight Explorer supports analysis of disease burden,

Real-world data and insight With our Explorer solution, we enable researchers and life sciences teams to query, explore and analyse near real-time, longitudinal data at speed — helping derive market insights, generate understanding and optimise healthcare delivery. Explorer securely streams data from multiple point of care systems across our network into a single analytics environment. This provides governed access to a rich, longitudinal dataset spanning care settings, enabling population level analysis within robust information governance and compliance frameworks. Real-world data Explorer provides access to high quality, deidentified clinical data drawn from across the care ecosystem. By bringing data from routine clinical practice into a single analytical environment, it supports flexible exploration of patterns in care delivery, treatment use and outcomes at scale.

prevalence, progression and outcomes across large, diverse patient populations. This enables organisations to quantify unmet need, understand patient journeys and identify opportunities to improve outcomes across

Key stats: • 38+ million patient records • 55 billion clinical observations • Data refreshed daily • Core data controller supporting OpenSAFELY during COVID 19

pathways, conditions and care settings. Variation, equity and system performance analysis

Explorer enables detailed analysis of variation, equity and system performance across geographies and populations. By revealing unwarranted variation and health inequalities, it supports more targeted, equitable and system wide improvement. Together, these capabilities support faster, more confident insight generation — and better informed decisions across research, market insight and healthcare delivery.

Explore the full brochure to find out more.

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Our impact

End-to-end lifecycle support From research and feasibility through to implementation and real-world evidence. Secure and governed by design Permission‑based, de‑identified data aligned to NHS and regulatory standards.

Optum supports progress across research, care and outcomes — delivering value for every part of the healthcare system.

For life sciences organisations • More predictable, scalable studies • Faster, more effective post‑launch delivery • Stronger evidence for access and adoption For patients • Earlier identification and intervention • Access to research opportunities • Safer, more consistent, evidence‑aligned care

For healthcare professionals • In‑workflow guidance and earlier identification • Clearer treatment intent and safer prescribing • Lower workload through seamless integration

For researchers • Faster, more representative recruitment • Real‑world pathway and service evaluation • High‑quality, near real‑time evidence For the NHS and ICBs • Reduced unwarranted variation • Scaled population‑level improvement • Real‑time insights for policy and pathway decisions

Trusted across the ecosystem

By clinicians, the NHS, researchers and leading life sciences organisations.

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Let’s bring innovation closer to patients

When Optum’s capabilities come together, life sciences organisations can:

Plan smarter

Recruit faster

Launch more effectively

Drive equitable implementation

Prove real-world impact sooner

Ready to bring innovation into everyday care? talk to our team .

info@emishealth.com

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Egton Medical Information Systems Ltd (t/a Optum) is a company registered in England and Wales. Registered number: 02117205. Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. © 2026 Optum. All rights reserved.